fastMRI: Region-Aware Image Reconstruction

Improving accelerated MRI reconstruction quality by applying a region-weighted loss function to deep learning models.

PyTorch
PyTorch Lightning
NumPy
Pandas
May 1, 2025

Image Similarity (SSIM)

Before

0.7653

After

0.7970

Higher is Better improvement

Pixel Error (NMSE)

Before

0.0078

After

0.0075

Lower is Better improvement

Signal Quality (PSNR)

Before

31.8660

After

32.1300

Higher is Better improvement

Project Overview

The foundational fastMRI project has already had a massive real-world impact, cutting scans that once took over 30 minutes down to less than 5. My work builds on this success, tackling the core challenge: how to reconstruct highly accurate images from severely undersampled k-space data.


To solve this, I enhanced Meta's baseline U-Net (a Convolutional Neural Network) by implementing a custom 'ROI-weighted' loss function. This upgrade strategically directs the model's focus to the clinically important Region-of-Interest (ROI), improving reconstruction accuracy where it matters most. I validated the approach first with a simple, centered ROI, then evolved it using a Sobel filter for more dynamic edge-based detection.


The foundational success set the stage for the main goal: applying the same logic to a state-of-the-art Cold Diffusion model. By enhancing this powerful algorithm with the ROI-weighted technique, we achieved high-impact results, demonstrating a significant boost in image quality across all key metrics.


The ROI-weighted model (right) reconstructs the image with visibly higher detail and accuracy, outperforming the baseline model (center) and closely matching the original ground truth (left).

Tags
Data & AI
fastMRI: Region-Aware Image Reconstruction | Luis Tupac